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Healthful Weight Loss




Calorie Restriction Weight Loss The CR Way


We take time to get to know you and help you use the revolutionary tools that are provided as part of this supportive CR Diet weight loss plan membership:

•  CR Way 4 Longer Life Edition Software

• CR Way to Happy Dieting Quick Start Guide

• Eatsmart Pro Kitchen Scale

• Best selling book, The CR Way

• Hands-on Teleconferences

• Access to exclusive content on livingTheCRWay.com

You'll start with the CR Way to Happy Dieting downloaded to your home computer. This quick start guide introduces a whole new happy, fun way of healthful dieting. Soon it will be natural to say "No, thank you" when someone offers you unhealthful food that will only add pounds and clog your arteries.




CR Way Healthful Weight Loss Membership comes with advanced CR diet and lifestyle software that takes the guesswork out of your new, healthful approach to calorie restriction weight loss. The Nutribase CR Way Edition Software is loaded with delicious recipes and suggested and foods to choose.

A first step is to show you how to activate healthful fat burning. This is not a CR diet plan that increases metabolic rate, which has been shown to shorten life and increases disease risk.The CR Way Diet plan activates the ancient defense system that resides within you for times when calories and glucose levels are low.

Calorie Restriction Diet and Overall Health

Soon your cells will become supercharged for energy efficiency. Your body will replace fat storage with fat burning. and empower you with energy, optimism and good health.

Life will be better as you feel like doing more.And your doctor will be amazed at how rapidly your overall health improves.

Become a Calorie Restriction Healthful Weight Loss Member and get started on calorie restriction healthful weight loss for a better, longer life!

And be sure to learn about our other great memberships, including calorie restriction longevity level and calorie restriction diabetes intervention.

For those who want to know more about how the CR Way helps activate the fat burning that facilitates weight loss, take a look at this study:

Low Sirt1 expression, which is upregulated by fasting,in human adipose

( fat) tissue from obese women.

Pedersen SB, Olholm J, Paulsen SK, Bennetzen MF, Richelsen B.

International Journal of Obesity advance online publication, 17 June 2008; doi:10.1038/ijo.2008.78



Long-term total fasting (6 days) of nine human volunteers increased Sirt1 mRNA expression in subcutaneous adipose tissue more than twofold (0.197-0.454 arbitrary units, P

Likewise, lean women (n=12) had more than twofold higher Sirt1 expression in subcutaneous adipose tissue compared to obese women (n=12; 0.33-0.73 arbitrary units, P



Human adipose tissue contains Sirt1 and the expression of Sirt1 can be regulated by calorie restriction as in other species. Furthermore, we demonstrated that resveratrol affects human fat-cell metabolism similar to the effects in rodents (that is, increased epinephrine induced lipolysis). These findings indicated that the beneficial effects of calorie restriction in humans might involve the activation of Sirt1. Thus, based on these findings, we propose that Sirt1 might play important roles for the beneficial effects of calorie restriction in humans.

PMID: 18560370


And this one too, showing that cellular fat receptors are blocked, which facilitates fat burning:

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.

Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L.

Nature. 2004 Jun 17;429(6993):771-6.

Calorie restriction extends lifespan in organisms ranging from yeast to mammals. In yeast, the SIR2 gene mediates the life-extending effects of calorie restriction. Here we show that the mammalian SIR2 orthologue, Sirt1 (sirtuin 1), activates a critical component of calorie restriction in mammals; that is, fat mobilization in white adipocytes. Upon food withdrawal Sirt1 protein binds to and represses genes controlled by the fat regulator PPAR-gamma (peroxisome proliferator-activated receptor-gamma), including genes mediating fat storage. Sirt1 represses PPAR-gamma by docking with its cofactors NCoR (nuclear receptor co-repressor) and SMRT (silencing mediator of retinoid and thyroid hormone receptors). Mobilization of fatty acids from white adipocytes upon fasting is compromised in Sirt1+/- mice. Repression of PPAR-gamma by Sirt1 is also evident in 3T3-L1 adipocytes, where overexpression of Sirt1 attenuates adipogenesis, and RNA interference of Sirt1 enhances it. In differentiated fat cells, upregulation of Sirt1 triggers lipolysis and loss of fat. As a reduction in fat is sufficient to extend murine lifespan, our results provide a possible molecular pathway connecting calorie restriction to life extension in mammals. 

PMID: 15175761